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Topamax is being studied for use in weight loss and to help treat alcoholics. Treatment of migraine headaches has not been studied. This medicine. Treatment must be started under specialist care and continued under the supervision of a specialist. Topiramate can help reduce the frequency, severity, and duration of migraines. Topamax is used to prevent migraine headaches. This medication rarely may cause mood or behavior changes, such as phenytoin. Although still classified as an anticonvulsant, Topamax is mostly prescribed for the treatment of migraines and sometimes as an antidepressant.
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