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Prednisolone works by acting within cells to prevent the release of substances in the body and, in order to be effective, first must be converted to Prednisolone by enzymes in the liver. It is not used in the management of adrenal insufficiency unless a more potent mineral corticoid is administered concomitantly. Steroid medication can weaken your immune system, making it easier for you to get an infection. Prednisone is less likely than other corticosteroids to be secreted in breast milk, but it should be ensured that if antibiotics are required, that they are given in effective doses.
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