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Because Baclofen is primarily removed from the body by the kidneys, people with reduced kidney function should be monitored by their doctor while taking Baclofen. To be adjusted when Baclofen is begun. Baclofen is the generic name for the anti-spastic medication Lioresal, which can lead to heavy sedation. Taking Baclofen. Baclofen drug can be administered either orally or directly into the spinal fluid. To assure safe balance and movement for certain activities.
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